Yes. Typical fecal coliform tests look for specific nutrient indicators produced by E. coli and fecal coliforms.  However, these nutrients can also be produced by other microbes, which can cause a false positive. 

With our tests, we are looking for the DNA of the host organism. We can specifically target the DNA of the host and then identify the quantity of DNA present in the sample to evaluate how serious the issue might be. Because our qPCR assays are highly specific to the host species, there's virtually no danger of non-specific amplifications.